Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Mytilene on Hotels.com. These Mytilene hotels consistently deliver on quality, location and traveler experience. Last updated on .
Hotels in Mytilene

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Where to stay in Mytilene?

1. Hotel Lesvion
Hotel LesvionLesvos
9.4 out of 10, Exceptional, (147 reviews)
$61 nightly
The price is $69
Nov 9 - Nov 10
Total with taxes and fees

2. Akti Vigla Premium
Akti Vigla PremiumLesvos
10.0 out of 10, Exceptional, (26 reviews)
$58 nightly
The price is $64
Nov 10 - Nov 11
Total with taxes and fees

3. Loriet Hotel
Loriet HotelLesvos
8.4 out of 10, Very good, (96 reviews)
$67 nightly
The price is $77
Nov 10 - Nov 11
Total with taxes and fees

4. Theofilos Paradise Boutique Hotel
Theofilos Paradise Boutique HotelLesvos
9.6 out of 10, Exceptional, (176 reviews)
$116 nightly
The price is $130
Nov 9 - Nov 10
Total with taxes and fees

5. Mythical Coast Wellness Retreat
Mythical Coast Wellness RetreatLesvos
8.6 out of 10, Excellent, (73 reviews)
$89 nightly
The price is $102
Nov 9 - Nov 10
Total with taxes and fees

6. Elysion Hotel
Elysion HotelLesvos
9.2 out of 10, Wonderful, (51 reviews)
$93 nightly
The price is $107
Nov 6 - Nov 7
Total with taxes and fees

7. Heliotrope Hotels
Heliotrope HotelsLesvos
8.6 out of 10, Excellent, (203 reviews)
$82 nightly
The price is $93
Nov 11 - Nov 12
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Showing deals for:Nov 6 - Nov 8

9.6 out of 10, Exceptional, (176 reviews)
We have 1 left at
$127 nightly
The price is $285
Total with taxes and fees
Showing deals for:Nov 13 - Nov 15

9.6 out of 10, Exceptional, (176 reviews)
We have 1 left at
$131 nightly
The price is $294
Total with taxes and fees
Showing deals for:Dec 5 - Dec 6
$14 off
$77 nightly
The price is $86
Total with taxes and fees
Check out pet-friendly hotels in Mytilene

9.6 out of 10, Exceptional, (176)
$116 nightly
The price is $130
Nov 9 - Nov 10
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Mytilene
Top landmarks in Mytilene
Learn more about Mytilene
Notable for its seaside, Mytilene features attractions such as Port of Mytilene and Mytilini Castle.

Check out reviews of Mytilene hotels guests love

Hotel Lesvion
10/10 Excellent
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