Excellent location! Easily accessible from the airport by boat (bus) without the need to lug luggage around in Venice like everybody else (trust me on this - there are no cars in venice and everybody are lugging their suitcases around). Easy checkin - we were in, unpacked and out walking before others got to their bus stop.
Area feels very safe, again, much safer than the packed areas elsewhere. Nearby supermarkets, fruit markets, daily fish market allowed us to take full advantage of the apartment kitchen. Many restaurants nearby, but take time to read reviews and decide where to go instead of just getting hailed in on the busy streets
Place was very clean. We appreciated to be able to sit down on the sofa and by the table where we enjoyed meals. Comfortable bed, plenty of hot water, shutters totally blocks light and allowed us to sleep uninterrupted.
We will definitely stay here again next time in Venice
Hint: When you buy your Alilaguna boat ticket in the airport, buy a roundtrip ticket! Tickets are not sold at the bus stops