This is a really great home base for a San Francisco visit. The cable car goes right past the front door, and takes you downtown to Market Street and the Ferry Building. There is a nice park right across the street, and the Fairmont Hotel's famous Tonga Room bar (worth visiting) is a block away.
The air conditioning was broken in the entire hotel during our stay. This wasn't a big deal for us, since the outdoor temps go down at night, but it might be worth asking about it when you book if you are someone who likes to manage the room temp with AC.
And the big caveat: the hotel's first two photos on this site are of a really nice-looking indoor pool. This was one of the reasons we booked it. But the pool isn't usable by any guests under 16. It is only usable from Fri-Sun if you book a spa treatment ($160 and up.) And during the week if you want to use the pool/whirlpool and are over 16, there is a $40 access fee. Just worth knowing before you book this hotel to use the pool...
The staff is really friendly and helpful. We booked a suite on the 8th floor and it was incredibly spacious, with great views. There is coffee and biscotti in the lobby every morning, and a bowl of fruit in the afternoon. We also had a rental car, and found free overnight parking spots in the neighborhood around the hotel pretty easily. Most of the spots allow you to park overnight for free, but you must move your car by 10 AM.