Business Hotels in Upstate South Carolina
Upstate South Carolina
Hotels in South Carolina
Hotels in United States of America
Hotels

Upstate South Carolina, South Carolina, United States of America

Business Hotels in Upstate South Carolina

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your current months are August, 2025 and September, 2025.

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Business Hotels in Upstate South Carolina

Woodspring Suites features a modern architectural design with a prominent entrance and a clear display of its name.

Relax in this stylish living room with a sofa, side tables, and a vibrant rug.

Compact kitchen with a refrigerator, microwave, and ample storage.

Guests can wash and dry their clothes in this convenient laundry facility.

Woodspring Suites Greenville Airport

2.5 star property

Greenville

8.6 out of 10, Excellent, (157)

8.6/10

Excellent

(157)

The price is ฿2,427

฿2,427

฿2,670 total

includes taxes & fees

9 Aug - 10 Aug

Woodspring Suites Greenville Airport

Relax by the fire pit surrounded by a tranquil water view.

Enjoy a meal at our central bar, surrounded by high tables and chairs, with TVs and a selection of food on display.

Welcome to our reception area, where friendly staff are available to assist with your stay.

Two single beds with white linens and decorative pillows, a desk, flat-screen TV, and a bathroom with sink and mirror.

Best Western Travelers Rest Greenville

2.5 star property

Travelers Rest

7.8 out of 10, Good, (1002)

7.8/10

Good

(1002)

The price is ฿3,025

฿3,025

฿3,328 total

includes taxes & fees

31 Aug - 1 Sept

Best Western Travelers Rest Greenville

Welcome to our reception area, featuring a sleek reception desk, comfortable seating, and a staircase leading to an upper level.

Conference room with a large flat-screen TV, white table, and eight chairs.

Enjoy meals and meetings in this well-equipped kitchen area with a central island and ample seating.

Relax in the serene patio area with a round table, four chairs, and a potted plant, surrounded by a small tree and a decorative fountain.

Inn @ Clemson

2.5 star property

Clemson

8.0 out of 10, Very good, (1005)

8.0/10

Very good

(1005)

The price is ฿3,851

฿3,851

฿4,274 total

includes taxes & fees

1 Sept - 2 Sept

Inn @ Clemson

Relax in the spacious lobby with a large seating area, central counter, and high ceiling.

Enter a welcoming space with a patterned carpet leading to a reception desk and unique design.

Welcome to Hampton Inn & Suites, featuring a modern entrance with a covered walkway and potted plants.

Relax in our spacious lobby with a cozy seating area, fireplace, and comfortable sofas.

Hampton Inn & Suites Greenville Airport, SC

2.5 star property

Greenville

9.2 out of 10, Wonderful, (927)

9.2/10

Wonderful

(927)

The price is ฿3,248

฿3,248

฿3,573 total

includes taxes & fees

5 Sept - 6 Sept

Hampton Inn & Suites Greenville Airport, SC

Enjoy meals and gatherings with friends and family in this lakeside patio area, surrounded by trees and a scenic view.

Relax by the rooftop pool surrounded by lounge chairs and tables, with a serene lake and forested hillside in the background.

Welcome to our lobby, featuring a reception desk, decorative wall piece, and comfortable seating area.

Relax in a stylish lounge area with a round table, comfortable armchairs, and a vibrant abstract painting.

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property

Seneca

9.4 out of 10, Exceptional, (181)

9.4/10

Exceptional

(181)

The price is ฿4,490

฿4,490

฿4,939 total

includes taxes & fees

19 Aug - 20 Aug

Fairfield Inn & Suites Seneca Clemson Univ Area

Indulge in a variety of dishes, including cheese omelets and sandwiches, at our buffet.

Reception area with a reception desk and geometric patterned wall.

Swimmers can enjoy the pool with depth indicators and lounge seating.

Relax in our inviting lobby with a comfortable seating area, large window, and beautiful artwork.

Holiday Inn Express Gaffney by IHG

2.5 star property

Gaffney

8.6 out of 10, Excellent, (346)

8.6/10

Excellent

(346)

The price is ฿2,519

฿2,519

฿2,746 total

includes taxes & fees

17 Aug - 18 Aug

Holiday Inn Express Gaffney by IHG

Enjoy a serene golf experience with a tranquil lake view.

Relax in a serene outdoor space surrounded by lush greenery and trees, with comfortable seating and tables.

Relax in this stylish living room with a large coffee table, two sofas, and a comfortable armchair.

Welcome to the Clemson University James E. Marianna Inn, where guests can check in and enjoy the warm atmosphere.

Clemson University's James F. Martin Inn

3.0 star property

Clemson

9.6 out of 10, Exceptional, (916)

9.6/10

Exceptional

(916)

The price is ฿4,813

฿4,813

฿5,342 total

includes taxes & fees

2 Sept - 3 Sept

Clemson University's James F. Martin Inn

Welcome to our reception area, featuring a reception desk and a geometric patterned wall.

Cozy retreat with a large bed, two bedside tables, and a framed picture on the wall.

Enjoy a self-service beverage station with a variety of drinks, a waffle maker, and coffee machine.

Hotel entrance with a flat roof and series of windows, marked by a canopy and light fixture.

Best Western Seneca-Clemson

2.5 star property

Seneca

8.4 out of 10, Very good, (598)

8.4/10

Very good

(598)

The price is ฿3,026

฿3,026

฿3,328 total

includes taxes & fees

17 Aug - 18 Aug

Best Western Seneca-Clemson

Relax in a stylish outdoor seating area with comfortable chairs and potted plants, surrounded by a modern architectural structure.

Relax in our inviting lobby, featuring a comfortable seating area, stylish coffee table, and lush greenery.

Experience the contemporary style of this hotel, featuring a curved glass entrance and beautifully landscaped surroundings.

Enjoy meals in a stylish dining area with tables for solo or group dining, accompanied by lush greenery.

Hilton Greenville

3.5 star property

Greenville

8.0 out of 10, Very good, (1002)

8.0/10

Very good

(1002)

The price is ฿2,398

฿2,398

฿2,638 total

includes taxes & fees

16 Aug - 17 Aug

Hilton Greenville

Relax in a spacious room with a large bed, two bedside tables, and a beautiful dark blue artwork.

Experience the airy, multi-level atrium with high ceilings and expansive views from the balconies.

Relax in a stylish room with a flat-screen TV, comfortable seating area, and a large mirror.

Enjoy meals and social gatherings in this stylish, multi-level space with a central dining area and expansive windows.

Best Western Plus Clemson Hotel & Conference Center

2.5 star property

Clemson

8.2 out of 10, Very good, (1001)

8.2/10

Very good

(1001)

The price is ฿3,542

฿3,542

฿3,931 total

includes taxes & fees

2 Sept - 3 Sept

Best Western Plus Clemson Hotel & Conference Center

Enjoy meals in a spacious dining area with a large window offering views of the surrounding greenery.

Enjoy a peaceful retreat with a view of the playground and trees from the large window, accompanied by a cozy seating area and a touch of greenery.

Relax in a stylish room with a comfortable bed, seating area, and large window.

The Abernathy features a symmetrical facade with brick and wood paneling, evenly spaced windows, and a flat roof.

The Abernathy of Clemson

4.0 star property

Clemson

9.6 out of 10, Exceptional, (538)

9.6/10

Exceptional

(538)

The Abernathy of Clemson

Hotel entrance with a central entrance flanked by flagpoles, surrounded by well-maintained landscaping.

Enjoy a hearty breakfast spread with a variety of options, including cereal, bread, and hot beverages.

Welcome to our hotel lobby, featuring a reception desk with a vibrant LED display, comfortable seating areas and a clean, contemporary design.

Two beds with white linens and a throw blanket, a flat-screen TV, and a desk with a chair.

Comfort Suites Clinton near Presbyterian College

2.5 star property

Clinton

8.2 out of 10, Very good, (707)

8.2/10

Very good

(707)

The price is ฿3,093

฿3,093

฿3,573 total

includes taxes & fees

24 Aug - 25 Aug

Comfort Suites Clinton near Presbyterian College

Relax by the pool with lounge chairs and a lifeguard on duty.

Enjoy a comfortable stay with two single beds, a large flat-screen TV, and a spacious workspace.

Check-in at the reception desk, where friendly staff are ready to assist with your stay.

Staircase leads to an upper level with a wooden handrail and a door with a wooden frame.

Super 8 by Wyndham Greer/Spartanburg Area

2.0 star property

Greer

7.2 out of 10, Good, (490)

7.2/10

Good

(490)

The price is ฿2,036

฿2,036

฿2,300 total

includes taxes & fees

14 Aug - 15 Aug

Super 8 by Wyndham Greer/Spartanburg Area

Welcome to our hotel lobby, featuring a central reception desk surrounded by comfortable seating areas and a unique ceiling design.

Relax in a cozy outdoor seating area with a sofa, coffee table, and fire feature under a covered pergola.

Experience the sleek design of this hotel, featuring a flat roof and symmetrical facade with multiple windows.

Two single beds with a textured duvet cover, wooden headboard, and nightstand with a lamp. A desk and chair, flat-screen TV, and window with a decorative valance complete the space.

Tru by Hilton Greenville Woodruff Road

2.5 star property

Greenville

9.2 out of 10, Wonderful, (227)

9.2/10

Wonderful

(227)

The price is ฿2,993

฿2,993

฿3,597 total

includes taxes & fees

7 Sept - 8 Sept

Tru by Hilton Greenville Woodruff Road

Welcome to our reception area, featuring a modern design with a warm glow, wood, and metal elements.

Relax in our spacious lobby with a central seating area, bar, and TV.

Welcome to the Holiday Inn Express, featuring a modern design and covered entrance.

Relax by the pool surrounded by lush greenery and enjoy a safe and comfortable stay.

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

2.5 star property

Anderson

9.0 out of 10, Wonderful, (555)

9.0/10

Wonderful

(555)

The price is ฿3,327

฿3,327

฿3,693 total

includes taxes & fees

7 Sept - 8 Sept

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Relax in the serene outdoor living area, featuring a comfortable sofa set, coffee table, and fire feature, surrounded by lush greenery and a beautiful tree.

Relax in this elegantly designed living area with a neutral-toned sofa, chandelier, and fireplace.

Relax in a spacious room with a large bed, flat-screen TV, and comfortable sofa.

Relax by the pool surrounded by lounge chairs and umbrellas, with a view of the surrounding landscape.

Hilton Garden Inn Greenville

3.0 star property

Greenville

9.0 out of 10, Wonderful, (968)

9.0/10

Wonderful

(968)

The price is ฿3,267

฿3,267

฿3,702 total

includes taxes & fees

22 Aug - 23 Aug

Hilton Garden Inn Greenville

Classic architecture meets elegant entrance at the AC Hotel Spartanburg.

Enjoy a drink at the bar, where you can sit and take in the city view.

Relax in style with comfortable seating and panoramic views of the city.

Relax in a stylish space with a comfortable sofa, small table, and a bed with a wooden headboard.

AC Hotel by Marriott Spartanburg

3.5 star property

Spartanburg

9.2 out of 10, Wonderful, (559)

9.2/10

Wonderful

(559)

The price is ฿4,167

฿4,167

฿4,717 total

includes taxes & fees

31 Aug - 1 Sept

AC Hotel by Marriott Spartanburg

Relax in the hotel's outdoor lounge area, featuring sofas, chairs, and a long bench, surrounded by lush greenery and fire pits.

Relax by the hotel's shallow pool, surrounded by lounge chairs and a glass barrier.

Relax in our welcoming lobby, featuring a reception area with a coffee machine, refrigerator, and toaster, as well as a cozy seating area with a table and chairs.

Relax in the stylish lobby, where sofas and armchairs invite socializing and a unique tree design adds artistic flair.

SpringHill Suites by Marriott Greenville Downtown

2.5 star property

Greenville Downtown

9.6 out of 10, Exceptional, (1001)

9.6/10

Exceptional

(1001)

The price is ฿3,592

฿3,592

฿3,951 total

includes taxes & fees

17 Aug - 18 Aug

SpringHill Suites by Marriott Greenville Downtown

Relax and socialize under the pergola, surrounded by wicker chairs and a stone fire pit.

Relax by the pool surrounded by lush greenery and comfortable lounge chairs.

Embassy Suites Greenville Golf Resort & Conference Center

3.5 star property

Greenville

8.8 out of 10, Excellent, (1000)

8.8/10

Excellent

(1000)

The price is ฿3,542

฿3,542

฿4,013 total

includes taxes & fees

17 Aug - 18 Aug

Embassy Suites Greenville Golf Resort & Conference Center

Enter through the elegant archway into a warm and inviting space.

Relax in a spacious room with a large bed, dresser, and comfortable seating area.

Relax in style amidst a classic design, with ample seating and elegant artwork.

Cozy living area with a dining table for six, fireplace, and comfortable seating.

The Bleckley Inn

3.5 star property

Anderson

9.8 out of 10, Exceptional, (400)

9.8/10

Exceptional

(400)

The price is ฿7,962

฿7,962

฿8,838 total

includes taxes & fees

7 Sept - 8 Sept

The Bleckley Inn

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Upstate South Carolina

Clemson University

If you'd like to get a taste of Clemson student life, check out Clemson University, located 0.5 mi (0.9 km) from central Clemson.

See propertiesSee properties in Clemson University

Lake Keowee

Listen to the relaxing sound of the water and take some great holiday pics at Lake Keowee, located 9 mi (14.6 km) from central Salem.

See propertiesSee properties in Lake Keowee

Falls Park on the Reedy

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

See propertiesSee properties in Falls Park on the Reedy

Fred W. Symmes Chapel

You can find out about the history of Cleveland with a visit to Fred W. Symmes Chapel. Wander the lakeside and forests in this relaxing area.

See propertiesSee properties in Fred W. Symmes Chapel

Bob Jones University

Enjoy the student vibe when you visit Bob Jones University during your travels in Greenville. Attend a sporting event or visit the shops in this family-friendly area.

See propertiesSee properties in Bob Jones University

Devils Fork State Park

You can take time to visit Devils Fork State Park during your travels to Salem. Wander the lakeside or discover the area's mountain views.

See propertiesSee properties in Devils Fork State Park

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Upstate South Carolina Hotels with Parking
Upstate South Carolina Hotels with WiFi
Upstate South Carolina Family Hotels
Upstate South Carolina Hotels with Free Breakfast
Upstate South Carolina Hotels with a Pool
Upstate South Carolina Hotels with a Gym
Upstate South Carolina Pet friendly Hotels
Upstate South Carolina Cheap Hotels

Turtlehead Hotels
Green Avenue Hotels
Pine Ridge Point Hotels
Chickasaw Point Hotels
Payne-Logan Hotels
Serenity Bay Hotels
Indian Oaks Hotels
Cliff Ridge Colony Hotels
Keowee Plantation Hotels
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Hotels near Clemson University
Hotels near BMW Performance Center
Hotels near Falls Park on the Reedy
Hotels near Bon Secours Wellness Arena
Hotels near Greenville Convention Center
Hotels near Haywood Mall
Hotels near The Peace Center
Hotels near Wofford College
Hotels near Prisma Health Greenville Memorial Hospital
Hotels near Fred W. Symmes Chapel
Hotels near Bob Jones University
Hotels near Devils Fork State Park
Hotels near Memorial Stadium
Hotels near Furman University
Hotels near Table Rock State Park
Hotels near Fluor Field at the West End
Hotels near WestGate Mall
Hotels near Anderson University
Hotels near Spartanburg Memorial Auditorium
Hotels near Heritage Park

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Hotels near Greenville-Spartanburg Intl. Airport (GSP)

The Westin Poinsett Greenville
Hyatt Place Greenville/Haywood
Comfort Inn & Suites Clemson - University Area
The Shepherd Hotel Downtown Clemson
Hampton Inn & Suites Greenville-Downtown-RiverPlace
Courtyard by Marriott Greenville Downtown
Quality Inn & Suites Greenville - Haywood Mall
Embassy Suites by Hilton Greenville Downtown Riverplace
Hotel Hartness
ECHO Suites Extended Stay by Wyndham Spartanburg
Urban Boutique Hotel, BW Signature Collection
Comfort Suites At WestGate Mall
Spartanburg Marriott
Holiday Inn Express & Suites Greenville - Downtown by IHG
AC Hotel By Marriott Greenville
Baymont by Wyndham Greenville Woodruff Rd
Days Inn by Wyndham Spartanburg Waccamaw
Holiday Inn Express Gaffney by IHG
WoodSpring Suites Spartanburg - Duncan
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Tru by Hilton Spartanburg
Fairfield Inn & Suites Seneca Clemson Univ Area
Comfort Inn & Suites Greer - Greenville
Holiday Inn Express & Suites Greenville Airport by IHG
Quality Inn Seneca Clemson Area US-123
Hampton Inn & Suites Seneca-Clemson Area
Baymont by Wyndham Easley/Greenville
Best Western Travelers Rest Greenville
Holiday Inn Express & Suites Clemson by IHG
The Inn at Patrick Square
Baymont by Wyndham Gaffney
Postcard Cabins Lake Hartwell
WoodSpring Suites Greenville Simpsonville
Fairfield Inn & Suites by Marriott Greenville Simpsonville
Quality Inn Simpsonville - Greenville
Holiday Inn Express & Suites Greenville S- Piedmont by IHG
Holiday Inn Express & Suites Greenville-Spartanburg (Duncan) by IHG
Hampton Inn Greenville/Travelers Rest

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Business Hotels in Upstate South Carolina

Check prices for these dates

Business Hotels in Upstate South Carolina

Woodspring Suites Greenville Airport

Woodspring Suites Greenville Airport

Top landmarks in Upstate South Carolina

Clemson University

Lake Keowee

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