Verified
10/10 Exceptional
Jan 21, 2026
Shaunte
Shaunte, 1-night trip
Hilton Jacksonville At Mayo Clinic
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Photo gallery for Hilton Jacksonville At Mayo Clinic
Reviews
9.49.4 out of 10
Exceptional
When you stay at Hilton Jacksonville At Mayo Clinic, you'll be within a 10-minute drive of Mayo Clinic Florida and St. Johns Town Center. The outdoor pool is a great spot to take a dip, and guests can grab a bite to eat at Coastal Kitchen, which serves American cuisine and is open for breakfast, lunch, and dinner. Other highlights at this luxurious hotel include a fitness center and a bar/lounge.
$159 nightly
The total price is $181
$181 total
May 25 - May 26
Total with taxes and fees
Popular amenities
- Pool
- Free WiFi
- Restaurant
- Air conditioning
- Gym
Room options
Check availability for these dates
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Showing 19 of 19 rooms
View all photos for Room, 1 King Bed
Room, 1 King Bed
9.09.0 out of 10
Wonderful
7 reviews
(7 reviews)
- Sleeps 2
- 1 King Bed
- Free WiFi
View all photos for Deluxe Room, 1 King Bed (Water View)
Deluxe Room, 1 King Bed (Water View)
- Water view
- Sleeps 2
- 1 King Bed
- Free WiFi
View all photos for Deluxe Room, 1 King Bed, Accessible (Roll-In Shower)
Deluxe Room, 1 King Bed, Accessible (Roll-In Shower)
- Sleeps 2
- 1 King Bed
- Free WiFi
View all photos for Junior Suite, 1 King Bed
Junior Suite, 1 King Bed
- Sleeps 4
- 1 King Bed
- Free WiFi
View all photos for Junior Suite, 1 King Bed, Corner
Junior Suite, 1 King Bed, Corner
- Sleeps 4
- 1 King Bed
- Free WiFi
View all photos for Junior Suite, 1 King Bed, Accessible (Roll-In Shower)
Junior Suite, 1 King Bed, Accessible (Roll-In Shower)
- Sleeps 2
- 1 King Bed
- Free WiFi
View all photos for Junior Suite, 1 King Bed, Accessible (Roll-In Shower)
Junior Suite, 1 King Bed, Accessible (Roll-In Shower)
- Sleeps 2
- 1 King Bed
- Free WiFi
View all photos for Suite, 1 King Bed, Accessible (Mobility & Hearing, Roll-In Shower)
Suite, 1 King Bed, Accessible (Mobility & Hearing, Roll-In Shower)
- Sleeps 2
- 1 King Bed
- Free WiFi
View all photos for Room, 1 King Bed (Water View)
Room, 1 King Bed (Water View)
9.09.0 out of 10
Wonderful
2 reviews
(2 reviews)
- Water view
- Sleeps 2
- 1 King Bed
- Free WiFi
View all photos for Room, 1 King Bed (Water View, Roll-In Shower)
Room, 1 King Bed (Water View, Roll-In Shower)
- Water view
- Sleeps 2
- 1 King Bed
- Free WiFi
View all photos for Room, 1 King Bed, Accessible (Hearing)
Room, 1 King Bed, Accessible (Hearing)
- Sleeps 2
- 1 King Bed
- Free WiFi
View all photos for Room, 1 King Bed, Accessible (Roll-In Shower)
Room, 1 King Bed, Accessible (Roll-In Shower)
- Sleeps 2
- 1 King Bed
- Free WiFi
View all photos for Room, 1 King Bed, Accessible (Hearing)
Room, 1 King Bed, Accessible (Hearing)
10.010.0 out of 10
Exceptional
1 review
(1 review)
- Sleeps 2
- 1 King Bed
- Free WiFi
View all photos for Room, 2 Queen Beds
Room, 2 Queen Beds
9.69.6 out of 10
Exceptional
23 reviews
(23 reviews)
- Sleeps 4
- 2 Queen Beds
- Free WiFi
View all photos for Room, 2 Queen Beds, Accessible (Water View, Hearing)
Room, 2 Queen Beds, Accessible (Water View, Hearing)
- Water view
- Sleeps 4
- 2 Queen Beds
- Free WiFi
View all photos for Room, 2 Queen Beds, Accessible, Bathtub
Room, 2 Queen Beds, Accessible, Bathtub
10.010.0 out of 10
Exceptional
1 review
(1 review)
- Sleeps 4
- 2 Queen Beds
- Free WiFi
View all photos for Room, 2 Queen Beds, Accessible (Hearing)
Room, 2 Queen Beds, Accessible (Hearing)
9.09.0 out of 10
Wonderful
2 reviews
(2 reviews)
- Sleeps 4
- 2 Queen Beds
- Free WiFi
View all photos for Room, 2 Queen Beds (Water View)
Room, 2 Queen Beds (Water View)
10.010.0 out of 10
Exceptional
1 review
(1 review)
- Water view
- Sleeps 4
- 2 Queen Beds
- Free WiFi
View all photos for Room, 2 Queen Beds, Accessible, Bathtub (View)
Room, 2 Queen Beds, Accessible, Bathtub (View)
- Sleeps 4
- 2 Queen Beds
- Free WiFi
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About the neighborhood
4745 Transformation Way, Jacksonville, FL, 32224
What's nearby
- University of North Florida - 5 min drive - 8.3 km
- St. Johns Town Center - 7 min drive - 12.0 km
- TPC Sawgrass - 16 min drive - 13.7 km
- Mayport Naval Station - 25 min drive - 19.2 km
- Jacksonville Naval Air Station - 28 min drive - 48.1 km
Getting around
- Jacksonville, FL (CRG-Jacksonville Executive at Craig) - 14 min drive
- Jacksonville International Airport (JAX) - 33 min drive
- St. Augustine, FL (UST-Northeast Florida Regional) - 41 min drive
- Jacksonville Station - 28 min drive
- Free area shuttle
Restaurants
- ‪Culver’s - ‬3 min drive
- ‪Starbucks - ‬3 min drive
- ‪Circle K - ‬16 min walk
- ‪M Brothers at Mayo - ‬14 min walk
- ‪Starbucks - ‬13 min walk
About this property
Hilton Jacksonville At Mayo Clinic
- When you stay at Hilton Jacksonville At Mayo Clinic, you'll be within a 10-minute drive of Mayo Clinic Florida and St. Johns Town Center. The outdoor pool is a great spot to take a dip, and guests can grab a bite to eat at Coastal Kitchen, which serves American cuisine and is open for breakfast, lunch, and dinner. Other highlights at this luxurious hotel include a fitness center and a bar/lounge.
At a glance
Hotel size
- 252 rooms
- Arranged over 8 floors
Arriving/Leaving
- Check-in start time: 4:00 PM; Check-in end time: 5:00 AM
- Express check-out available
- Late check-in subject to availability
- Minimum check-in age: 21
- Check-out time is 11:00 AM
- Contactless check-out available
Special check-in instructions
- Front desk staff will greet guests on arrival at the property
- If you are planning to arrive after 11:00 PM please contact the property in advance using the information on the booking confirmation
- The credit card used to book the reservation must be presented by the cardholder at check-in along with matching photo identification, and other arrangements must be coordinated with the property prior to arrival
- Information provided by the property may be translated using automated translation tools
Required at check-in
- Credit card required for incidental charges
- Government-issued photo ID may be required
- Minimum check-in age is 21
Children
- Up to 2 children (18 years old and younger) stay free, per registered adult, when occupying the parent or guardian's room, using existing bedding
Pets
- Pets not allowed
Internet
- Free WiFi in public areas
- Free WiFi in rooms (speed: 25+ Mbps)
Parking
- Uncovered onsite self parking (USD 12.00 per night)
- Electric vehicle charging point on site
Offsite
- Free area shuttle within 350 yards
Other information
- Smoke-free property
Property amenities
Food and drink
- Buffet breakfast (surcharge) each morning 6:00 AM–10:30 AM
- Restaurant
- Bar/lounge
- Room service (late night)
Traveling with children
- Children stay free (see details)
- Free local shuttle
- Grocery/convenience store
- Children's menu
Working away
- 12 meeting rooms
- Coworking spaces
- Conference space (20000 square feet)
Services
- 24-hour front desk
- Concierge services
- Dry cleaning/laundry services
- Luggage storage
- Wedding services
- Porter/bellhop
- Pool loungers
- Pool umbrellas
- Romance packages
Facilities
- 1 building/tower
- Built in 2025
- Television in common areas
- Fitness center
- An outdoor pool
- At least 80% of food locally-sourced
- Vegetarian dining options
- At least 80% lighting from LEDs
- Comprehensive food waste policy
- Firepit
- Outdoor furniture
- Traditional architecture
Accessibility
- Tile flooring in public areas
Room amenities
Be entertained
- 55-inch Smart TV
- Premium cable channels
- Netflix
- Streaming services
Home comfort
- Air conditioning and heating
- Coffee/tea maker
- Iron/ironing board
Sleep well
- Blackout drapes/curtains
- Premium bedding
- Free crib/infant bed
- Rollaway/extra bed (surcharge)
Freshen up
- Bathtub or shower
- Soap and shampoo
- Hair dryer
- Towels
- Toilet paper
Stay connected
- Free WiFi (speed of 25+ Mbps)
- Free long-distance and local calls
Food and drink
- Mini-fridge
- Free bottled water
More
- Daily housekeeping
- In-room safe (laptop compatible)
- LED light bulbs
- Recycling
- Water-efficient showers only
- Water-efficient toilets only
- Mobile key entry
- Local maps
Special features
Dining
Coastal Kitchen - This restaurant specializes in American cuisine and serves breakfast, lunch, and dinner. Guests can enjoy drinks at the bar. A children's menu is available.
Coastal Kitchen Bar - Onsite cocktail bar. Open daily.
Fees & policies
Refundable deposits
- Breakage deposit: USD 100 per day
Optional extras
- Buffet breakfast is offered for an extra charge of approximately USD 26.99 to 26.99 for adults, and USD 15 to 30 for children
Children & extra beds
- Rollaway beds are available for USD 50.00 per night
Parking
- Uncovered self parking costs USD 12.00 per night
Pool, spa, & gym (if applicable)
- Pool access available from 8:00 AM to 10:00 PM
- Guests under 21 years old are not allowed in the fitness facility, and guests under 16 years old are only allowed in the swimming pool with adult supervision
Policies
Only registered guests are allowed in the guestrooms.
Guests can rest easy knowing there's a carbon monoxide detector, a fire extinguisher, and a smoke detector on site.
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation.
This property accepts credit cards and debit cards. Cash is not accepted.
Credit cards accepted: Visa, Mastercard, American Express, Discover, Diners Club, Carte Blanche
Cashless transactions are available.
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
Also known as
Hilton Jacksonville At Mayo Clinic Hotel
Hilton Jacksonville At Mayo Clinic Jacksonville
Hilton Jacksonville At Mayo Clinic Hotel Jacksonville
Frequently asked questions
Is there a pool at Hilton Jacksonville At Mayo Clinic?
Yes, there's an outdoor pool. Guests have pool access from 8:00 AM to 10:00 PM.
Are pets allowed at Hilton Jacksonville At Mayo Clinic?
Sorry, pets aren't allowed.
Is parking offered on site at Hilton Jacksonville At Mayo Clinic?
Yes. Self parking costs USD 12.00 per night. Electric vehicle charging is available.
What are the check-in and check-out times at Hilton Jacksonville At Mayo Clinic?
Check-in start time: 4:00 PM; Check-in end time: 5:00 AM. Check-out time is 11:00 AM. Express check-out and contactless check-out are available.
What is there to do at Hilton Jacksonville At Mayo Clinic and nearby?
Hilton Jacksonville At Mayo Clinic has an outdoor pool and a fitness center.
Are there restaurants at or near Hilton Jacksonville At Mayo Clinic?
Yes, Coastal Kitchen offers American cuisine.
What's the area around Hilton Jacksonville At Mayo Clinic like?
Hilton Jacksonville At Mayo Clinic is located a short 6-minute walk from Mayo Clinic Florida.
Have a question?
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Reviews
Hilton Jacksonville At Mayo Clinic Reviews
9.4
Exceptional
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
9.8
Cleanliness
9.4
Amenities
9.6
Staff & service
9.8
Property conditions & facilities
Guest review summary
What guests liked
- Breakfast offered a great variety and was well worth the cost with home-cooked, extensive offerings. (4 reviews)
- Parking was easy and convenient with a free shuttle service to nearby destinations. (3 reviews)
From real guest reviews summarized by AI.
Reviews
Verified
10/10 Exceptional
Mar 10, 2026
Very clean and room was nice
Thomas
Thomas, 2-night trip
Verified
10/10 Exceptional
Feb 2, 2026
Good restaurant, convenient location for Mayo Clinic, easy parking.
Maria Ines
Maria Ines, 3-night trip
Verified
10/10 Exceptional
Jan 4, 2026
Room was spotless, amenities were great, and staff was super nice!
Mark
Mark, 5-night trip
Verified
10/10 Exceptional
Jan 9, 2026
Clean rooms, friendly staff close to Mayo Clinic.
Schylea
Schylea, 2-night trip
Verified
10/10 Exceptional
Dec 30, 2025
Beautiful, clean, great atmosphere, very nice staff!
Julie
Julie, 2-night trip
Verified
10/10 Exceptional
Jan 25, 2026
Loved this hotel! Great location - friendly staff- yummy food and drinks at Coastal restaurant- hire and rooms are so nice and clean - pool and gym area were a plus! Coffee spot and shuttle also nice to have available.
Daisy
Daisy, 3-night trip
Verified
10/10 Exceptional
Jan 21, 2026
The rooms were clean. Bar staff were wonderful, great personalities.
Melissa
Melissa, 3-night trip
Verified
10/10 Exceptional
Oct 17, 2025
Great staff and rooms
Albert
Albert, 1-night trip
Verified
10/10 Exceptional
Feb 10, 2026
Friendly welcoming staff at the front desk and the restaurant! Immaculate! Comfy bedding and pillows!
Diane
Diane, 1-night trip
Verified
10/10 Exceptional
Oct 27, 2025
Very nice hotel. Food is excellent and friendly staff.
Erron
Erron, 2-night trip
Verified
10/10 Exceptional
Dec 21, 2025
Yes very clean beautiful and nice staff. Conveniently located to Mayo.
Gary
Gary, 2-night trip
Verified
10/10 Exceptional
Nov 2, 2025
Clean, comfortable, nice restaurant & coffee shop.
Joahnna
Joahnna, 3-night trip
Verified
10/10 Exceptional
Jan 25, 2026
Newly constructed, very clean and well maintained. Great staff. Highly recommend.
Mohsin
Mohsin, 1-night trip
Verified
10/10 Exceptional
Jan 19, 2026
The hotel looks like brand new! Modern and clean.
Christian
Christian, 1-night trip
Verified
10/10 Exceptional
Oct 31, 2025
Spotless rooms, very friendly service!
DEBORAH
DEBORAH, 4-night trip
Verified
10/10 Exceptional
Jan 29, 2026
Nice room
Samuel
Samuel, 2-night trip
Verified
10/10 Exceptional
Jan 7, 2026
Beautiful hotel! Very comfortable beds. Spotless!! Definitely recommend. A+++++
Catherine
Catherine, 1-night trip
Verified
10/10 Exceptional
Dec 17, 2025
Room was great and spacious. hoteal and bar staff was very accomodating
michael
michael, 1-night trip
Verified
8/10 Very good
Dec 30, 2025
The staff were courteous, the amenities fantastic. Only problem was a clump of hair from a previous guest found in the shower.
Tristan
Tristan, 1-night trip
Verified
10/10 Exceptional
Nov 2, 2025
Room was spotless, new hotel, wonderful friendly staff
Cathy
Cathy, 1-night trip
Verified
10/10 Exceptional
Dec 10, 2025
Room was amazing. Staff friendly and very knowledgeable!
Carrie
Carrie, 1-night trip
Verified
10/10 Exceptional
Dec 22, 2025
Staff was friendly. Room was clean. Little wait at checkin. Bed was great!
Jo-Ann
Jo-Ann, 1-night trip
Verified
10/10 Exceptional
Nov 10, 2025
Very nice facility and staff. Would recommend to anyone visiting the Mayo Clinic.
Shearn
Shearn, 2-night trip
Verified
10/10 Exceptional
Dec 2, 2025
Clean. Very friendly staff.
Mark
Mark, 1-night trip