Holiday Inn Express & Suites St. Louis South - I-55 by IHG

St. Louis hotel with indoor pool and 24-hour fitness

Choose dates to view prices

Where to?

Dates

October 2025

November 2025

Standard Room, 2 Queen Beds, Accessible (Mobil Tub) | In-room safe, desk, laptop workspace, blackout drapes

Holiday Inn Express & Suites St. Louis South - I-55, an IHG Hotel is a hub of activity in the business district. Start your day with a hearty breakfast buffet and stay connected with in-room WiFi, then unwind by the indoor pool or keep fit at the 24-hour gym.

Exceptional

Popular amenities

Pool
Non-smoking
Connecting rooms available
24/7 front desk

Main amenities (9)

Daily housekeeping
Indoor pool
24-hour fitness center
Business center
Meeting rooms
24-hour front desk
Front-desk safe
Vending machine
Banquet hall

Feel at home (6)

Free cribs/infant beds
Microwave
Connecting/adjoining rooms available
Private bathroom
Television
Daily housekeeping

$111 nightly

Oct 19 - Oct 20

Total with taxes and fees

Room options

Check availability for these dates

Tonight

Oct 14 - Oct 15

Tomorrow

Oct 15 - Oct 16

All rooms

1 bed

2 beds

Showing 10 of 10 rooms

Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

Exceptional

Highlights

Air conditioning

Heating

Connecting rooms available

Free cribs/infant beds

Refrigerator

Flat-screen TV

Blackout drapes/curtains

Private bathroom

300 sq ft
Sleeps 4
2 Queen Beds

Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

Exceptional

Highlights

Air conditioning

Heating

Connecting rooms available

Free cribs/infant beds

Refrigerator

Flat-screen TV

Blackout drapes/curtains

Hair dryer

300 sq ft
Sleeps 4
2 Queen Beds

Suite, 1 Bedroom (2 Queen, Extra Living Area)

Exceptional

Highlights

Air conditioning

Heating

Connecting rooms available

Free rollaway/extra beds

Free cribs/infant beds

Refrigerator

Flat-screen TV

Blackout drapes/curtains

300 sq ft
Sleeps 6
2 Queen Beds

Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

Wonderful

Highlights

Air conditioning

Heating

Connecting rooms available

Free cribs/infant beds

Refrigerator

Flat-screen TV

Blackout drapes/curtains

Private bathroom

300 sq ft
Sleeps 4
1 King Bed

Free toiletries, hair dryer, towels, soap

Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

Exceptional

Highlights

Air conditioning

Heating

Connecting rooms available

Free cribs/infant beds

Refrigerator

Flat-screen TV

Blackout drapes/curtains

Private bathroom

300 sq ft
Sleeps 2
1 King Bed

Suite, 1 King Bed (Extra Living, Walk in Shwr)

Wonderful

Highlights

Air conditioning

Heating

Connecting rooms available

Free rollaway/extra beds

Free cribs/infant beds

Refrigerator

Flat-screen TV

Blackout drapes/curtains

300 sq ft
Sleeps 4
1 King Bed

Standard Room, 1 King Bed (Bath Shwr Combo)

Exceptional

Highlights

Air conditioning

Heating

Connecting rooms available

Free cribs/infant beds

Refrigerator

Flat-screen TV

Blackout drapes/curtains

Private bathroom

300 sq ft
Sleeps 4
1 King Bed

Standard Room

Highlights

Air conditioning

Heating

Connecting rooms available

Free cribs/infant beds

Refrigerator

Flat-screen TV

Blackout drapes/curtains

Private bathroom

300 sq ft
Sleeps 2
1 Twin Bed

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

Highlights

Air conditioning

Heating

Connecting rooms available

Free rollaway/extra beds

Free cribs/infant beds

Refrigerator

Flat-screen TV

Blackout drapes/curtains

300 sq ft
Sleeps 4
1 King Bed

Standard Room, 2 Queen Beds

Exceptional

Highlights

Air conditioning

Heating

Connecting rooms available

Free cribs/infant beds

Refrigerator

Flat-screen TV

Blackout drapes/curtains

Private bathroom

300 sq ft
Sleeps 4
2 Queen Beds

Similar properties

Pool
Pet friendly
Free parking
Restaurant

$117 nightly

Oct 31 - Nov 1

Total with taxes and fees

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About the neighborhood

4250 Midamerica Lane, St. Louis, MO, 63129

What's nearby

Barnes Jewish South Campus - 5 min walk - 0.4 km
Mercy Hospital South - 5 min drive - 4.6 km
Grant's Farm - 11 min drive - 9.4 km
River City Casino - 11 min drive - 12.1 km
Magic House - St. Louis Children's Museum - 13 min drive - 16.8 km

Getting around

St. Louis Lambert Intl. Airport (STL) - 32 min drive
St. Louis, MO (SUS-Spirit of St. Louis) - 32 min drive
Kirkwood Station - 17 min drive
St. Louis Gateway Station - 19 min drive

Restaurants

‪Burger King - ‬10 min walk
‪Popeyes Louisiana Kitchen - ‬4 min walk
‪Starbucks - ‬9 min walk
‪Rich & Charlie's Italian Restaurant - ‬3 min drive
‪Hardee's / Red Burrito - ‬11 min walk

About this property

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

When visiting St. Louis, Holiday Inn Express & Suites St. Louis South - I-55 by IHG is a great choice to consider. For a bit of exercise, you can visit the 24-hour fitness center or go for a swim in the indoor pool. Fellow travelers say great things about the helpful staff and breakfast.

At a glance

Hotel size

- 99 rooms
- Arranged over 4 floors

Arriving/Leaving

- Check-in start time: 3:00 PM; Check-in end time: 2:30 AM
- Minimum check-in age: 21
- Check-out time is 11 AM
- Contactless check-out available

Special check-in instructions

- Front desk staff will greet guests on arrival at the property

Required at check-in

- Credit card, debit card, or cash deposit required for incidental charges
- Government-issued photo ID may be required
- Minimum check-in age is 21

Pets

- Pets not allowed
- Service animals welcome

Internet

- Free WiFi in public areas
- Free WiFi and wired internet access in rooms

Parking

- Free onsite self parking
- Wheelchair-accessible parking and van parking on site

Other information

- Smoke-free property

Property amenities

Food and drink

Free buffet breakfast each morning 6:00 AM–9:30 AM

Working away

Business center
Meeting rooms

Services

24-hour front desk
Pool loungers

Facilities

Safe-deposit box at front desk
24-hour fitness center
An indoor pool
At least 10% of profits reinvested in community & sustainability
No plastic drinking straws
Banquet hall

Accessibility

Elevator
Wheelchair-accessible path of travel
Wheelchair-accessible parking
Wheelchair-accessible public washroom
Wheelchair-accessible concierge desk
Wheelchair-accessible van parking
Wheelchair-accessible path to elevator
Wheelchair-accessible pool
Wheelchair-accessible fitness center
Wheelchair-accessible lounge
Visual alarms in hallways
Closed captioned TV
Well-lit path to entrance
Stair-free path to entrance

Room amenities

Be entertained

49-inch flat-screen TV
Cable TV channels

Home comfort

Air conditioning (climate-controlled) and heating
Coffee/tea maker
Iron/ironing board

Sleep well

Blackout drapes/curtains
Free crib/infant bed
Bed sheets provided

Freshen up

Private bathroom
Free toiletries
Hair dryer
Towels
Toothbrush and toothpaste (on request)
Toilet paper

Stay connected

Desk
Free WiFi and wired internet
Free local calls

Food and drink

Refrigerator
Microwave

Daily housekeeping
In-room safe
Connecting/adjoining rooms available

Fees & policies

Pool, spa, & gym (if applicable)

Pool access available from 8 AM to 10 PM

Policies

The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.

This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

This property accepts credit cards. Cash is not accepted.

Credit cards accepted: Visa, Mastercard, American Express, Discover, Diners Club, JCB International, Carte Blanche

This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

Also known as

Holiday Inn Express St. Louis South I-55 Hotel

Holiday Inn Express St. Louis South I-55

Inn Express St Louis I55

Holiday Inn Express Suites St. Louis South I 55

Holiday Inn Express Suites St. Louis South I 55 by IHG

Holiday Inn Express Suites St. Louis South I 55 an IHG Hotel

Holiday Inn Express & Suites St. Louis South - I-55 by IHG Hotel

Frequently asked questions

Does Holiday Inn Express & Suites St. Louis South - I-55 by IHG offer free cancellation for a full refund?

Yes, Holiday Inn Express & Suites St. Louis South - I-55 by IHG does have fully refundable room rates available to book on our site. If you’ve booked a fully refundable room rate, this can be cancelled up to a few days before check-in depending on the property's cancellation policy. Just make sure to check this property's cancellation policy for the exact terms and conditions.