If you're looking for a place to get away, look no further than Cayo Guillermo. Whether you're planning to stay for a night or for the week, the area around Cayo Guillermo has accommodation options to fit every need. Search for hotels in Cayo Guillermo with Hotels.com by checking our online map. Our map displays the areas and neighbourhoods around all Cayo Guillermo hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Cayo Guillermo hotel deals are here with our lowest price guarantee.
Hotels with Smoking Rooms in Cayo Guillermo
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Hotels with Smoking Rooms in Cayo Guillermo
Club Cayo Guillermo - All Inclusive
Club Cayo Guillermo - All Inclusive
6.0 out of 10, (1)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top landmarks in Cayo Guillermo
Cayo Guillermo Beach
If being by the water is a major draw, Cayo Guillermo Beach is a spot you might want to check out, located 2.1 mi (3.4 km) from central Cayo Guillermo.
Cayo Guillermo Marina
Cayo Guillermo Marina is worth a visit, located 2.6 mi (4.2 km) from central Cayo Guillermo.