Luxury Hotels in Mytilene

Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices

Check prices for these dates

Tonight
Feb 26 - Feb 27
Tomorrow
Feb 27 - Feb 28
This weekend
Feb 28 - Mar 2
Next weekend
Mar 7 - Mar 9

Luxury Hotels in Mytilene

Top landmarks in Mytilene

Port of Mytilene

Imagine strolling along Port of Mytilene for some great waterfront pics when in the heart of Mytilene. If you carry on walking you'll get to Plaz Tsamákia and Fykiótrypa for some more water views.

See properties in Port of Mytilene
Port of Mytilene

Frequently asked questions

What are the cheapest luxury hotels in Mytilene?
Choose one of the affordable luxury hotels in Mytilene that promise upscale stays at savvy prices. Simply select the “Luxury Property” checkbox, then fine-tune your search by setting the maximum amount you want to pay. Also, think about timing. Going away during off-peak seasons can help you save. To earn discounts on future bookings, be sure to sign up for One Key™, our rewards program.
What is the best time to stay in a luxury hotel in Mytilene?
When deciding when to stay in a luxury hotel in Mytilene, consider the weather, tourist seasons and if any major local events are on. These will impact costs, crowds and the experiences you’ll have. Also, think about your own preferences, including whether you prefer lively peak times or quieter off-seasons.
What are the best 5-star luxury hotels in Mytilene?
Experience service that’s a cut above the rest at Elysion Hotel. This 5-star luxury Mytilene hotel has everything you need and more, including a swimming pool and a furnished balcony.
Are there any luxury hotels in Mytilene with parking?
Look up luxury hotels in Mytilene that feature room for your ride by selecting the “Parking” filter. It’s located under “Amenities.” No need to circle the block for a spot or compromise on convenience — at these stays you can simply park and go.